![](https://chfs-en.hzau.edu.cn/wp-content/uploads/2022/07/Nie-Bihua.jpeg)
Degree: Ph.D.
Title: Associate Professor
Graduation School: Huazhong Agricultural University
Office: 720, North Building
Nie Bihua, a native of Wuhan, Hubei province, currently serves as an associate professor and master’s supervisor in the Department of Vegetable Sciences at the College of Horticulture and Forestry Sciences, Huazhong Agricultural University. He is a core researcher at the Key Laboratory of Potato Biology and Biotechnology (MARA), Hubei Potato Engineering and Technology Research Center, and a post expert of the Modern Agricultural Industrial Technology System of Hubei Province. His research primarily focuses on applied and fundamental studies of potato-virus interaction and resistance. He has led and participated in over 20 scientific research projects, including 3 projects funded by the National Natural Science Foundation of China. Nie Bihua has authored more than 30 research articles in prestigious journals such as Plant Biotechnology Journal, Horticulture Research, and Plant Disease. Additionally, he has obtained 2 invention patents, developed 3 new potato varieties, and received 2 Hubei Provincial Science and Technology Progress Awards.
[1] 2005.09-2010.12 College of Horticulture and Forestry Sciences, Huazhong Agricultural University > PhD Horticulture
[2] 1999.09-2002.06 College of Horticulture and Forestry Sciences, Huazhong Agricultural University > MS Horticulture
[3] 1995.09-1999.06 Department of Horticulture, Hunan Agricultural University > BS Agriculture
[1] 2012.12-present> Huazhong Agricultural University>Associate Professor
[2] 2008.12-2010.08> Agriculture and Agri-Food Canada, Potato Research Center> Visiting scholar
[3] 2004.10-2012.11> Huazhong Agricultural University>Lecturer
[4] 2002.07-2004.09> Huazhong Agricultural University>Teaching assistant
1) Islam S, Li J, Rahman M A, Xie F, Song B, Nie B*. Resistance to Common Potato Diseases: the Origin of the Genes and Corresponding Molecular Markers. Phytopathology Research, 2024, 6:4. DOI: 10.1186/s42483-023-00222-9
2) Zhan X, Tu Z, Song W, Nie B, Li S, Zhang J, Zhang F*. Cas13a-based multiplex RNA targeting for potato virus Y. Planta, 2023, 258, 70. https://doi.org/10.1007/s00425-023-04216-x
3) Zhan X, Liu W, Nie B, Zhang F*, Zhang J*. Cas13d-mediated multiplex RNA targeting confers a broad-spectrum resistance against RNA viruses in potato. Communications Biology, 2023, 6, 855. https://doi.org/10.1038/s42003-023-05205-2
4) Liu T, Md Abu Kawochar, Shahnewaz Begum, Wang E, Zhou T, Jing S, Liu T, Yu L, Nie B*, Song B* Potato tonoplast sugar transporter 1 controls tuber sugar accumulation during 1 postharvest cold storage. Horticulture Research, 2023,10: uhad035
5) Li J, Tu W, Xiao G, Liu T, Chen H, Tao W, Nie B*, Song B*. Pleiotropic QTL underlying the dormancy and reducing sugar content in potato tubers uncovered by conditional QTL analysis. Potato Research, 2023,66:965-979. https://doi.org/10.1007/s11540-022-09606-4
6) Chen R, He C, Nie X, Tu Z, Kun Li, Fei S, Song B, Nie B*, Xie C. Susceptibility factor StEXA1 interacting with StnCBP facilitates the accumulation of potato virus Y in potato through the stress granules dependent RNA regulatory pathway. Horticulture Research, 2022, uhac159, https://doi.org/10.1093/hr/uhac159
7) Chen R, Yang M, Tu Z, Xie F, Chen J, Luo T, Hu X, Nie B*, He C*. Eukaryotic translation initiation factor 4E family member nCBP facilitates the accumulation of TGB-encoding viruses by recognizing the viral coat protein in potato and tobacco. Front. Plant Sci. 2022, doi: 10.3389/fpls.2022.946873
8) Li K, Chen R, Tu Z, Nie X, Song B, He C, Xie C, Nie B*. Global screening and functional identification of major HSPs involved in PVY infection in potato. Genes 2022, 13, 566. https://doi.org/ 10.3390/genes13040566
9) Huang W#, Nie B#*, Tu Z, Li C, Murphy A, Singh M, Song B, Zhang S, Xie C, Nie X*. Extreme resistance to potato virus A in potato cultivar Barbara is independently mediated by Ra and Rysto. Plant Dis. 2021, 105(11): 3344-3348. https://doi.org/10.1094/PDIS-02-21-0233-SC
10) Zhang H, Zhao Z, Nie B, Lyu C, Liu X*. Selenium loss and changes in product quality during cooking of selenium enriched potato tubers. Journal of Food Composition and Analysis, 2021, 96: 103728
11) Liu X, Chen L, Shi W, Xu X, Li Z, Liu T, He Q, Xie C, Nie B*, Song B. Comparative transcriptome reveals distinct starch-sugar interconversion patterns in potato genotypes contrasting for cold-induced sweetening capacity. Food Chemistry, 2021, 334(1): 127550
12) Nie X*, Singh M, Chen D, Gilchrist C, Soqrat Y, Shukla M, Creelman A, Dickison V. Nie B, Lavoie J, Bisht V. Development of High Resolution DNA Melting Analysis for Simultaneous Detection of Potato Mop-Top Virus and Its Vector, Spongospora subterranea, in Soil. Plant Dis. 2021, 105(4): 948-957.
13) Zhang H, Liu X, Song B, Nie B, Zhang W, Zhao Z*. Effect of excessive nitrogen on levels of amino acids and sugars, and differential response to post-harvest cold storage in potato (Solanum tuberosum L.) tubers. Plant Physiology and Biochemistry, 2020, 157: 38-46
14) Zhang H, Zhao X, Zhang X, Yang B, Yu Y, Liu T, Nie B*, Song B*. Functional analysis of an anthocyanin synthase gene StANS in potato. Scientia Horticulturae 2020, 272(15):109569
15) Wang Y, Chen R, Nie X, Zhong Z, Li C, Li K, Huang W, Fu X, Liu J and Nie B*. Rapid and sensitive detection of Potato virus Y by isothermal reverse transcription-recombinase polymerase amplification assay in potato. Molecular and Cellular Probes, 2020, 50:101505.
16) Zhan X#, Zhang F#, Zhong Z#, Chen R, Wang Y, Chang L, Bock R, Nie B*, Zhang J*. Generation of virus-resistant potato plants by RNA genome targeting. Plant Biotechnology Journal, 2019, 17: 1817-1822.
17) Nie X*, Dickison V, Brooks S, Nie B, Singh M, De Koeyer D L, Murphy A. High resolution DNA melting assays for detection of Rx1 and Rx2 for high-throughput marker-assisted selection for extreme resistance to Potato virus X in tetraploid potato. Plant Dis. 2018, 102(2): 382-390.
18) Wang J, Meng F, Chen R, Liu J, Nie X, Nie B*. RT-PCR differentiation, Molecular and Pathological Characterization of Andean and Ordinary Strains of Potato virus S in Potatoes in China. Plant Dis. 2016, 100(8):1580-1585.
19) Nie X*, Liang Z, Nie B, Murhpy A, Singh M. Studies on varietal response to different strains of Potato virus Y (PVY) reveal hypersensitive resistance in Exploits to PVYO and extreme resistance in F87084 to all tested strains. Am. J. Potato Res. 2015, 92:23-31.
20) Yang L, Nie B, Liu J, Song B*. A Reexamination of the Effectiveness of Ribavirin on Eradication of Viruses in Potato Plantlets in vitro Using ELISA and Quantitative RT-PCR. Am. J. Potato Res. 2014, 91:304-311.
21) Nie B, Singh M, Murphy A, Sullivan A, Xie C, and Nie X*. Response of potato cultivars to five isolates belonging to four strains of Potato virus Y. Plant Dis. 2012, 96:1422-1429.
22) Nie B, Singh M, Sullivan N, Singh R P, Xie C and Nie X*. Recognition and molecular discrimination of severe and mild PVYO variants of Potato virus Y in potatoes in New Brunswick, Canada. Plant Dis. 2011, 95:113-119.
1) Liu Jun; Zhu Lihua; Xie Suli; Cai Xingkui; Nie Bihua. A method for efficient and energy-saving production of potato tissue culture seedlings. January 9, 2018, China, ZL 2015 1 0530844.1
2) Nie Bihua; Huang Wei; Song Botao; Tu Zhen; Li Chunyan. Molecular marker and application of Indel linked to extreme resistance gene Ra of potato virus A. May 3, 2022, China, CN202110138307.8
3) Nie Bihua; Luo Tao; Chen Ruhao; Song Botao; Li Jiana; Xu Binyan. Primers for detecting potato virus X (PVX) and potato virus Y (PVY) and their applications in qPCR and ddPCR virus detection. December 1, 2023, China, 202311635368.0
4) Nie Bihua; Chen Ruhao; Tu Zhen; Yang Manhua; Chen Jiaru; Xie Fangru. Application of the StpCaP1 gene in enhancing resistance of potatoes to PVY and PVS viruses. December 25, 2023, China, 2023118116834